FTSJ3

Across TCGA patient cohorts, FTSJ3 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FTSJ3-associated genes across cancer lineages are PCNA, MEK1, and mTOR_pS2448. Each is linked with FTSJ3 in more than 2 cancer types. Because this analysis shows association rather than direction, both FTSJ3-to-partner and partner-to-FTSJ3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by FTSJ3-low versus FTSJ3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FTSJ3→partner) and Y-score (partner→FTSJ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.283	+2.584	<.001	.001	3	3
UCEC	MEK1 →	+0.345	+2.700	.013	.005	3	2
UCEC	mTOR_pS2448 →	-0.124	-2.202	.029	.010	3	2
UCEC	Rictor_pT1135 →	-0.097	-2.584	.013	.010	3	2
UCEC	TFRC →	+0.488	+2.459	.016	.018	3	2
UCEC	TIGAR →	+0.120	+2.114	.040	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

PCNA by FTSJ3 expression — UCEC

Explore this box plot interactively →