FTSJ3

Across TCGA cell cohorts, FTSJ3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,043 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FTSJ3-associated GO terms across cancer lineages are Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Maturation of SSU-rRNA, and Regulation of transcription by RNA polymerase I. Each is linked with FTSJ3 in more than 16 cancer types. Because this analysis shows association rather than direction, both FTSJ3-to-partner and partner-to-FTSJ3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by FTSJ3-low versus FTSJ3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FTSJ3→partner) and Y-score (partner→FTSJ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.117	+0.961	<.001	<.001	3	17
BLOOD_Lymphoma	Maturation of SSU-rRNA →	+0.128	+1.114	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription by RNA polymerase I →	+0.101	+1.175	.001	<.001	3	16
BONE	Positive regulation of DNA-directed DNA polymerase activity →	+0.246	+0.932	.001	.002	3	15
BLOOD_Lymphoma	Positive regulation of transcription by RNA polymerase I →	+0.099	+0.957	<.001	<.001	3	15
BLOOD_Lymphoma	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.107	+0.897	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,043 associations by consensus.

Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by FTSJ3 expression — BLOOD_Lymphoma

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