FTMT

Across TCGA pan-cancer cohorts, FTMT RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of FTMT’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where FTMT RNA is repressed in tumor relative to normal tissue. In most cancer types FTMT is over-expressed in tumor, although a few such as BRCA and HNSC show the opposite, repressed pattern.

BRCA, HNSC, and COAD are the cancer types where FTMT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FTMT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	−0.392	<.001	6	view →
HNSC	All	IV	−0.028	.023	2	view →
COAD	Male	All	−0.036	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

FTMT–BRCA

Open the BRCA breakdown →