Across TCGA pan-cancer cohorts, FTLP4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of FTLP4’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where FTLP4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FTLP4 is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.
COAD and LUAD are the cancer types where FTLP4 tumor–normal differential expression is most reproducible.