Across TCGA pan-cancer cohorts, FTLP12 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of FTLP12’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where FTLP12 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FTLP12 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.
LIHC, KICH, and KIRC are the cancer types where FTLP12 tumor–normal differential expression is most reproducible.