FTLP10

Across TCGA patient cohorts, FTLP10 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,006 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FTLP10-associated GO terms across cancer lineages are Negative regulation of muscle cell apoptotic process, Desmosome organization, and Regulation of integrin biosynthetic process. Each is linked with FTLP10 in more than 8 cancer types. Because this analysis shows association rather than direction, both FTLP10-to-partner and partner-to-FTLP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of muscle cell apoptotic process grouped by FTLP10-low versus FTLP10-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FTLP10→partner) and Y-score (partner→FTLP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of muscle cell apoptotic process →	+0.059	+0.845	<.001	<.001	3	9
CESC	Desmosome organization →	+0.063	+0.411	<.001	<.001	3	7
ESCA	Regulation of integrin biosynthetic process →	+0.107	+0.517	<.001	<.001	3	7
ESCA	Keratinocyte proliferation →	+0.059	+0.766	<.001	<.001	3	7
STAD	Polysaccharide catabolic process →	+0.076	+0.175	<.001	.002	3	6
STAD	Nucleolar large rRNA transcription by RNA polymerase I →	+0.066	+0.148	<.001	.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,006 associations by consensus.

Negative regulation of muscle cell apoptotic process by FTLP10 expression — ESCA

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