FTL

Across TCGA pan-cancer cohorts, FTL Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FTL data layer compared with 23 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher FTL Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FTL expression acts as an unfavorable survival marker.

STAD and KIRP are the cancer types where FTL Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	II,III,IV	0.183	0.660	.009	12	view →
KIRP	DFS	Median	All	0.178	0.867	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

FTL–STAD (OS)

Open the STAD breakdown →