FTL

Across TCGA patient cohorts, FTL RNA expression is significantly associated with the protein abundance of many other proteins, with 17,679 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FTL-associated proteins across cancer lineages are GPNMB, NCF2, and NPL. Each is linked with FTL in more than 7 cancer types. Because this analysis shows association rather than direction, both FTL-to-partner and partner-to-FTL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FTL versus GPNMB in GBM, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FTL→partner) and Y-score (partner→FTL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GPNMB →	+1.175	+1.026	<.001	<.001	3	8
GBM	NCF2 →	+0.893	+1.034	<.001	<.001	3	7
GBM	NPL →	+0.889	+1.103	<.001	<.001	3	7
GBM	PLD3 →	+0.425	+0.635	.001	.009	3	7
OV	APBB1IP →	+0.650	+0.666	<.001	<.001	3	7
GBM	MPP1 →	+0.472	+0.951	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,679 associations by consensus.

FTL vs GPNMB — GBM

Explore this scatter interactively →