FTL

Across TCGA patient cohorts, FTL protein abundance is significantly associated with the RNA expression of many other genes, with 11,568 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FTL-associated genes across cancer lineages are VSIG4, CCR1, and HMOX1. Each is linked with FTL in more than 7 cancer types. Because this analysis shows association rather than direction, both FTL-to-partner and partner-to-FTL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FTL versus VSIG4 in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FTL→partner) and Y-score (partner→FTL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VSIG4 →	+1.207	+0.827	.001	<.001	3	8
UCEC	CCR1 →	+1.070	+0.844	<.001	<.001	3	8
GBM	HMOX1 →	+1.110	+0.908	<.001	<.001	3	7
GBM	MS4A4A →	+1.011	+0.851	<.001	<.001	3	7
COAD	SIGLEC7 →	+0.745	+0.987	<.001	<.001	3	7
UCEC	CCL18 →	+2.587	+0.822	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,568 associations by consensus.

FTL vs VSIG4 — UCEC

Explore this scatter interactively →