FTL

Across TCGA patient cohorts, FTL protein abundance is significantly associated with the protein abundance of many other proteins, with 20,644 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FTL-associated proteins across cancer lineages are FTH1, FTH1_S179, and APOE. Each is linked with FTL in more than 9 cancer types. Because this analysis shows association rather than direction, both FTL-to-partner and partner-to-FTL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FTL versus FTH1 in CCRCC, with a Pearson correlation of 0.90.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FTL→partner) and Y-score (partner→FTL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FTH1 →	+1.464	+2.613	<.001	<.001	3	10
CCRCC	FTH1_S179 →	+1.483	+2.400	<.001	<.001	3	9
GBM	APOE →	+0.866	+1.376	<.001	<.001	3	8
GBM	HMOX1 →	+0.590	+0.970	<.001	<.001	3	8
UCEC	CD163 →	+0.908	+0.912	<.001	<.001	3	8
LSCC	SAFB →	-0.261	-0.762	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,644 associations by consensus.

FTL vs FTH1 — CCRCC

Explore this scatter interactively →