FTL

Across TCGA cell cohorts, FTL RNA expression is significantly associated with the go_rna of many other GO terms, with 5,402 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FTL-associated GO terms across cancer lineages are Response to nitrosative stress, Prostanoid metabolic process, and Cellular response to jasmonic acid stimulus. Each is linked with FTL in more than 11 cancer types. Because this analysis shows association rather than direction, both FTL-to-partner and partner-to-FTL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to nitrosative stress grouped by FTL-low versus FTL-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FTL→partner) and Y-score (partner→FTL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Response to nitrosative stress →	+0.136	+1.864	.002	<.001	3	12
LUNG_NSCLC_LUSC	Prostanoid metabolic process →	+0.196	+2.274	.001	<.001	3	11
OVARY	Cellular response to jasmonic acid stimulus →	+1.565	+2.197	<.001	<.001	3	11
OVARY	Response to jasmonic acid →	+1.565	+2.197	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Icosanoid metabolic process →	+0.116	+1.000	<.001	<.001	3	11
LIVER	Response to thyroxine →	+0.157	+1.855	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,402 associations by consensus.

Response to nitrosative stress by FTL expression — LIVER

Explore this box plot interactively →