FTHL17

Across TCGA patient cohorts, FTHL17 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,044 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible FTHL17-associated GO terms across cancer lineages are Telomerase RNA localization, Positive regulation of cell cycle checkpoint, and Positive regulation of telomerase RNA localization to Cajal body. Each is linked with FTHL17 in more than 9 cancer types. Because this analysis shows association rather than direction, both FTHL17-to-partner and partner-to-FTHL17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomerase RNA localization grouped by FTHL17-low versus FTHL17-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FTHL17→partner) and Y-score (partner→FTHL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Telomerase RNA localization →	+0.068	+0.329	<.001	.003	3	10
KIRP	Positive regulation of cell cycle checkpoint →	+0.066	+0.019	<.001	.002	3	9
STAD	Positive regulation of telomerase RNA localization to Cajal body →	+0.071	+0.257	<.001	.003	3	9
STAD	Negative regulation of chromosome organization →	+0.069	+0.186	<.001	.002	3	9
STAD	Chromosome localization →	+0.069	+0.174	<.001	.005	2	10
STAD	Metaphase chromosome alignment →	+0.077	+0.176	<.001	.004	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,044 associations by consensus.

Telomerase RNA localization by FTHL17 expression — STAD

Explore this box plot interactively →