FTHL17

Across TCGA patient cohorts, FTHL17 mutation is significantly associated with the RNA expression of many other genes, with 612 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FTHL17-associated genes across cancer lineages are RN7SKP286, MIR3616, and ARHGAP42P3. Each is linked with FTHL17 in more than 2 cancer types. Because this analysis shows association rather than direction, both FTHL17-to-partner and partner-to-FTHL17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP286 grouped by FTHL17-low versus FTHL17-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FTHL17→partner) and Y-score (partner→FTHL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP286 →	+0.040	+3.812	<.001	.008	3	3
SKCM	MIR3616 →	+0.238	+2.993	<.001	.004	3	3
SKCM	ARHGAP42P3 →	+0.008	+4.402	<.001	<.001	3	3
BRCA	RNU6-566P →	+1.527	+8.471	<.001	.005	3	2
UCEC	OBSCN-AS1 →	-0.520	-3.427	.006	.005	3	2
UCEC	DOLPP1 →	+0.539	+2.595	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 612 associations by consensus.

RN7SKP286 by FTHL17 expression — UCEC

Explore this box plot interactively →