FTHL17

Across TCGA cell cohorts, FTHL17 RNA expression is significantly associated with the mutation status of many other genes, with 97 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FTHL17-associated genes across cancer lineages are KRT83, HHIPL1, and OPA1. Each is linked with FTHL17 in more than 1 cancer types. Because this analysis shows association rather than direction, both FTHL17-to-partner and partner-to-FTHL17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT83 grouped by FTHL17-low versus FTHL17-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FTHL17→partner) and Y-score (partner→FTHL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	KRT83 →	+4.029	+0.026	.007	<.001	3	2
OVARY	HHIPL1 →	+4.222	+0.022	.006	<.001	3	2
LUNG_NSCLC_LUAD	OPA1 →	+2.959	+1.367	.004	<.001	3	2
LARGE_INTESTINE	PYCR3 →	+4.415	+0.060	.007	<.001	3	2
LARGE_INTESTINE	ANO2 →	+3.000	+0.032	.003	<.001	3	2
PANCREAS	AREG →	+4.029	+0.026	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

KRT83 by FTHL17 expression — PANCREAS

Explore this box plot interactively →