Across TCGA pan-cancer cohorts, FTH1P14 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of FTH1P14’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where FTH1P14 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FTH1P14 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.
LIHC and STAD are the cancer types where FTH1P14 tumor–normal differential expression is most reproducible.