FTH1

Across TCGA patient cohorts, FTH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,587 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FTH1-associated proteins across cancer lineages are ITGAM, ITGB2, and CYBB. Each is linked with FTH1 in more than 4 cancer types. Because this analysis shows association rather than direction, both FTH1-to-partner and partner-to-FTH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FTH1 versus ITGAM in GBM, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FTH1→partner) and Y-score (partner→FTH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ITGAM →	+0.728	+0.715	<.001	<.001	3	5
PDAC	ITGB2 →	+0.633	+0.597	<.001	<.001	3	5
PDAC	CYBB →	+0.582	+0.554	<.001	.001	3	5
OV	APOBR →	+0.494	+0.996	.001	.001	3	5
OV	IRF2BP1_S66 →	-0.754	-0.722	<.001	.006	3	4
PDAC	ITGA5 →	+0.534	+0.595	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,587 associations by consensus.

FTH1 vs ITGAM — GBM

Explore this scatter interactively →