FTH1

Across TCGA patient cohorts, FTH1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,272 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FTH1-associated genes across cancer lineages are BEST1, HMOX1, and SIGLEC9. Each is linked with FTH1 in more than 7 cancer types. Because this analysis shows association rather than direction, both FTH1-to-partner and partner-to-FTH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FTH1 versus BEST1 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FTH1→partner) and Y-score (partner→FTH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BEST1 →	+0.802	+0.634	<.001	<.001	3	8
GBM	HMOX1 →	+1.252	+0.542	<.001	<.001	3	7
COAD	SIGLEC9 →	+0.688	+0.441	<.001	<.001	3	7
COAD	ITGAX →	+0.919	+0.441	<.001	<.001	3	7
COAD	COLEC12 →	+1.211	+0.703	<.001	<.001	3	7
HNSC	CCR1 →	+0.986	+0.405	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,272 associations by consensus.

FTH1 vs BEST1 — GBM

Explore this scatter interactively →