FTCD

Across TCGA patient cohorts, FTCD mutation is significantly associated with the RNA expression of many other genes, with 1,278 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FTCD-associated genes across cancer lineages are MIR921, RNU5F-2P, and RAPGEF1. Each is linked with FTCD in more than 1 cancer types. Because this analysis shows association rather than direction, both FTCD-to-partner and partner-to-FTCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR921 grouped by FTCD-low versus FTCD-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FTCD→partner) and Y-score (partner→FTCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR921 →	+0.558	+4.788	<.001	.006	3	2
STAD	RNU5F-2P →	+0.432	+3.574	.003	.002	3	2
UCEC	RAPGEF1 →	+0.460	+2.447	<.001	.001	3	2
SKCM	MLX →	+0.433	+2.580	.003	.009	3	2
UCEC	DUSP3 →	+0.457	+1.895	<.001	.001	3	2
UCEC	APBA3 →	+0.337	+2.064	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,278 associations by consensus.

MIR921 by FTCD expression — BLCA

Explore this box plot interactively →