FTCD

Across TCGA cell cohorts, FTCD mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible FTCD-associated genes across cancer lineages are COX8C, ERVV-2, and LCE2A. Each is linked with FTCD in more than 1 cancer types. Because this analysis shows association rather than direction, both FTCD-to-partner and partner-to-FTCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX8C grouped by FTCD-low versus FTCD-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FTCD→partner) and Y-score (partner→FTCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	COX8C →	+0.091	+4.217	<.001	.005	3	2
STOMACH	ERVV-2 →	+0.238	+3.392	.001	.007	3	2
BLOOD_Leukemia	LCE2A →	+0.042	+4.384	<.001	.006	3	2
URINARY_TRACT	SEC14L3 →	+0.011	+4.217	<.001	.005	3	1
URINARY_TRACT	NOBOX →	+0.020	+5.044	<.001	<.001	3	1
URINARY_TRACT	LECT2 →	+0.848	+4.217	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

COX8C by FTCD expression — URINARY_TRACT

Explore this box plot interactively →