FSTL4

Across TCGA cell cohorts, FSTL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,267 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FSTL4-associated GO terms across cancer lineages are Regulation of proteasomal protein catabolic process, Response to mycotoxin, and ATP metabolic process. Each is linked with FSTL4 in more than 7 cancer types. Because this analysis shows association rather than direction, both FSTL4-to-partner and partner-to-FSTL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of proteasomal protein catabolic process grouped by FSTL4-low versus FSTL4-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FSTL4→partner) and Y-score (partner→FSTL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of proteasomal protein catabolic process →	+0.060	+0.345	<.001	.006	3	8
URINARY_TRACT	Response to mycotoxin →	+0.996	+1.895	.002	<.001	3	7
BLOOD_Lymphoma	ATP metabolic process →	+0.074	+0.337	<.001	.007	3	7
BREAST	Branching morphogenesis of an epithelial tube →	-0.094	-1.175	<.001	<.001	3	7
BREAST	Morphogenesis of a branching structure →	-0.061	-0.820	.002	<.001	3	7
LUNG_NSCLC_LUSC	Regulation of long-term synaptic potentiation →	-0.109	-1.546	.002	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,267 associations by consensus.

Regulation of proteasomal protein catabolic process by FSTL4 expression — BLOOD_Lymphoma

Explore this box plot interactively →