FSTL1

Across TCGA patient cohorts, FSTL1 mutation is significantly associated with the RNA expression of many other genes, with 2,618 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FSTL1-associated genes across cancer lineages are RN7SL371P, MIR4695, and RNU6-1084P. Each is linked with FSTL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FSTL1-to-partner and partner-to-FSTL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL371P grouped by FSTL1-low versus FSTL1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSTL1→partner) and Y-score (partner→FSTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL371P →	+0.232	+4.331	<.001	.007	3	3
LUAD	MIR4695 →	+0.423	+7.930	<.001	.008	3	3
UCEC	RNU6-1084P →	+0.077	+3.738	<.001	.009	3	3
UCEC	RNU6-1069P →	+0.671	+2.079	<.001	<.001	3	3
UCEC	LINC00869 →	-0.480	-2.668	<.001	.005	3	2
COAD	RN7SL598P →	+0.252	+3.294	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,618 associations by consensus.

RN7SL371P by FSTL1 expression — BLCA

Explore this box plot interactively →