Across TCGA patient cohorts, FSIP2 mutation is significantly associated with the total protein of many other genes, with 79 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FSIP2-associated genes across cancer lineages are Cyclin-B1, C-Raf, and ASNS. Each is linked with FSIP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FSIP2-to-partner and partner-to-FSIP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSIP2→partner) and Y-score (partner→FSIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.540	+2.523	<.001	<.001	3	6
UCEC	C-Raf →	+0.147	+1.398	<.001	.003	3	4
COAD	ASNS →	+0.750	+2.467	<.001	.011	3	4
UCEC	Caspase-7-cleavedD198 →	+0.512	+1.315	<.001	.005	3	4
UCEC	4E-BP1 →	+0.292	+2.523	<.001	<.001	3	4
LUAD	FASN →	+0.400	+3.321	.031	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 79 associations by consensus.

Exploration

FSIP2 survival (RNA) · tumor vs normal (RNA) · all FSIP2 data types