Across TCGA cell cohorts, FSIP2 mutation is significantly associated with the RNA expression of many other genes, with 1,260 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FSIP2-associated genes across cancer lineages are PSMF1, COX7C, and USP41. Each is linked with FSIP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FSIP2-to-partner and partner-to-FSIP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSIP2→partner) and Y-score (partner→FSIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PSMF1 →	-0.553	-1.676	.005	.006	3	3
SKIN	COX7C →	+0.355	+2.222	<.001	.001	3	3
LUNG_SCLC	USP41 →	-2.012	-3.321	<.001	<.001	3	3
SKIN	RPL15 →	+0.438	+2.222	<.001	.001	3	3
LUNG_NSCLC_LUAD	FAM81A →	+0.847	+2.584	<.001	.002	3	3
LUNG_NSCLC_LUAD	FDX2 →	-0.392	-2.807	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,260 associations by consensus.

Exploration

FSIP2 survival (RNA) · tumor vs normal (RNA) · all FSIP2 data types