FSD2

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FSD2 mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FSD2-associated genes across cancer lineages are Bromosporine, GSK2110183B, and 123829. Each is linked with FSD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FSD2-to-partner and partner-to-FSD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSD2→partner) and Y-score (partner→FSD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEBromosporine →+0.529+2.871<.001.02131
LARGE_INTESTINEGSK2110183B →+0.686+2.871.016.02131
LARGE_INTESTINE123829 →+0.745+2.871.006.02131
LARGE_INTESTINEKRAS (G12C) Inhibitor-12 →+0.729+2.868.001.02231
LARGE_INTESTINEGSK2606414 →+0.566+2.991.001.01821
LARGE_INTESTINEPRT062607 →+0.679+2.777.003.03021
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration