FSD1

Across TCGA pan-cancer cohorts, FSD1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FSD1 data layer compared with 27 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FSD1 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated FSD1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCEC show a favorable association.

LUAD, COAD, and PRAD are the cancer types where FSD1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	1.000	0.487	.024	13	view →
COAD	OS	Median	III,IV	0.167	0.799	<.001	9	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
UCEC	DFS	Median	II,III,IV	0.922	0.437	.028	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FSD1–LUAD (DFS)

Open the LUAD breakdown →