FSD1

Across TCGA cell cohorts, FSD1 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible FSD1-associated genes across cancer lineages are ZSCAN1, OR14A2, and OR2S2. Each is linked with FSD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FSD1-to-partner and partner-to-FSD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZSCAN1 grouped by FSD1-low versus FSD1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSD1→partner) and Y-score (partner→FSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ZSCAN1 →	+0.039	+5.000	<.001	.006	3	1
PANCREAS	OR14A2 →	+0.020	+5.614	<.001	.002	3	1
PANCREAS	OR2S2 →	+0.020	+5.614	<.001	.002	3	1
PANCREAS	TBL1Y →	+0.006	+5.614	<.001	.002	3	1
SKIN	KRTAP15-1 →	+0.050	+6.022	<.001	.001	3	1
LARGE_INTESTINE	CLDN17 →	+0.052	+3.930	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

ZSCAN1 by FSD1 expression — PANCREAS

Explore this box plot interactively →