FSCN3

Across TCGA patient cohorts, FSCN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,091 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FSCN3-associated GO terms across cancer lineages are Positive regulation of double-strand break repair via homologous recombination, DNA-templated transcription initiation, and Protein acetylation. Each is linked with FSCN3 in more than 30 cancer types. Because this analysis shows association rather than direction, both FSCN3-to-partner and partner-to-FSCN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair via homologous recombination grouped by FSCN3-low versus FSCN3-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FSCN3→partner) and Y-score (partner→FSCN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Positive regulation of double-strand break repair via homologous recombination →	+0.131	+0.271	<.001	<.001	3	31
STAD	DNA-templated transcription initiation →	+0.058	+0.089	<.001	<.001	3	29
SCLC	Protein acetylation →	+0.109	+0.254	<.001	<.001	3	29
STAD	Regulation of microtubule cytoskeleton organization →	+0.054	+0.097	<.001	<.001	3	29
STAD	Signal transduction by p53 class mediator →	+0.058	+0.086	<.001	<.001	3	29
STAD	Protein polymerization →	+0.052	+0.090	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,091 associations by consensus.

Positive regulation of double-strand break repair via homologous recombination by FSCN3 expression — SCLC

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