FSCN2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FSCN2 mutation is significantly associated with the RNA expression of many other genes, with 91 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FSCN2-associated genes across cancer lineages are OR8D2, MTCO3P16, and H2AP. Each is linked with FSCN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FSCN2-to-partner and partner-to-FSCN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSCN2→partner) and Y-score (partner→FSCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAOR8D2 →+0.065+6.618<.001.00132
COADMTCO3P16 →+0.117+4.308<.001.00932
KIRPH2AP →+0.077+5.301<.001.00332
UCECSNORD116-16 →+0.808+4.188.001.00932
UCECIGLVI-38 →+0.248+5.146<.001.00132
UCECMRPS22P1 →+0.077+4.937.009.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 91 associations by consensus.

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