Across TCGA cell cohorts, FSCN2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FSCN2-associated genes across cancer lineages are GZMK, HHLA1, and LEUTX. Each is linked with FSCN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FSCN2-to-partner and partner-to-FSCN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSCN2→partner) and Y-score (partner→FSCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GZMK →	+0.501	+4.037	.001	.004	3	1
BLOOD_Leukemia	HHLA1 →	+0.009	+3.551	<.001	.009	3	1
BREAST	LEUTX →	+0.367	+5.169	<.001	.005	3	1
LUNG_SCLC	OR13D1 →	+0.048	+4.269	<.001	.005	3	1
LUNG_SCLC	OR1G1 →	+0.171	+4.523	<.001	.003	3	1
LUNG_SCLC	GDF2 →	+0.017	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

FSCN2 survival (RNA) · tumor vs normal (RNA) · all FSCN2 data types