FSCN1

Across TCGA cell cohorts, FSCN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,992 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FSCN1-associated GO terms across cancer lineages are Positive regulation of podosome assembly, Microspike assembly, and Regulation of podosome assembly. Each is linked with FSCN1 in more than 18 cancer types. Because this analysis shows association rather than direction, both FSCN1-to-partner and partner-to-FSCN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of podosome assembly grouped by FSCN1-low versus FSCN1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FSCN1→partner) and Y-score (partner→FSCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of podosome assembly →	+1.963	+4.291	<.001	<.001	3	19
BLOOD_Lymphoma	Microspike assembly →	+1.394	+4.494	<.001	<.001	3	18
BREAST	Regulation of podosome assembly →	+0.673	+2.578	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Establishment of apical/basal cell polarity →	+0.232	+2.964	<.001	<.001	3	17
STOMACH	Establishment of monopolar cell polarity →	+0.183	+4.136	<.001	<.001	3	16
STOMACH	Establishment or maintenance of monopolar cell polarity →	+0.182	+4.029	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,992 associations by consensus.

Positive regulation of podosome assembly by FSCN1 expression — BREAST

Explore this box plot interactively →