FSCN1

Across TCGA cell cohorts, FSCN1 mutation is significantly associated with the mutation status of many other genes, with 4,772 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FSCN1-associated genes across cancer lineages are ABCC8, ZNF507, and ADRA1B. Each is linked with FSCN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FSCN1-to-partner and partner-to-FSCN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABCC8 grouped by FSCN1-low versus FSCN1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSCN1→partner) and Y-score (partner→FSCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ABCC8 →	+2.591	+3.263	.004	.004	1	4
SOFT_TISSUE	ZNF507 →	+4.502	+5.066	.007	.007	1	4
SOFT_TISSUE	ADRA1B →	+5.502	+5.502	.003	.003	1	4
BLOOD_Leukemia	SIAE →	+5.050	+4.000	.008	.008	1	4
BLOOD_Leukemia	LAMA4 →	+2.913	+4.063	<.001	<.001	1	4
BLOOD_Leukemia	MAP3K10 →	+3.050	+3.624	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,772 associations by consensus.

ABCC8 by FSCN1 expression — BLOOD_Leukemia

Explore this box plot interactively →