Across TCGA cell cohorts, FSCB mutation is significantly associated with the RNA expression of many other genes, with 501 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FSCB-associated genes across cancer lineages are PSMC6, PPA2, and LZIC. Each is linked with FSCB in more than 1 cancer types. Because this analysis shows association rather than direction, both FSCB-to-partner and partner-to-FSCB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSCB→partner) and Y-score (partner→FSCB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PSMC6 →	+0.402	+3.064	.005	.009	3	2
LARGE_INTESTINE	PPA2 →	+0.663	+3.386	<.001	.001	3	2
LARGE_INTESTINE	LZIC →	+0.537	+2.628	.001	.002	3	2
LARGE_INTESTINE	HPF1 →	+0.793	+2.628	<.001	.002	3	2
LARGE_INTESTINE	ACTR6 →	+0.605	+3.169	<.001	.009	3	2
BREAST	IFNL4 →	+0.029	+3.906	.007	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 501 associations by consensus.

Exploration

FSCB survival (RNA) · tumor vs normal (RNA) · all FSCB data types