FSBP

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FSBP Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FSBP data layer compared with 16 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher FSBP Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated FSBP expression acts as an unfavorable survival marker.

MESO are the cancer types where FSBP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESODFSMedianAll0.0990.392.0309view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

FSBP–MESO (DFS)

Kaplan–Meier survival curve for FSBP mutant vs wild-type samples in MESO.

Open the MESO breakdown →

Exploration