FRYL

Across TCGA patient cohorts, FRYL protein abundance is significantly associated with the RNA expression of many other genes, with 15,619 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FRYL-associated genes across cancer lineages are OCIAD2, COMMD8, and MCF2L-AS1. Each is linked with FRYL in more than 4 cancer types. Because this analysis shows association rather than direction, both FRYL-to-partner and partner-to-FRYL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRYL versus OCIAD2 in UCEC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRYL→partner) and Y-score (partner→FRYL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OCIAD2 →	+0.935	+0.178	<.001	.002	3	5
OV	COMMD8 →	+0.638	+0.272	<.001	<.001	3	5
LSCC	MCF2L-AS1 →	-0.875	-0.219	.001	<.001	3	5
GBM	MOAP1 →	-0.510	-0.229	.001	<.001	3	5
HNSC	EHBP1 →	-0.618	-0.288	<.001	<.001	3	4
HNSC	SWT1 →	-0.463	-0.229	.003	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,619 associations by consensus.

FRYL vs OCIAD2 — UCEC

Explore this scatter interactively →