FRY

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FRY RNA expression is significantly associated with the protein abundance of many other proteins, with 23,309 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FRY-associated proteins across cancer lineages are CRMP1, DDX21_S121, and EIF2S2. Each is linked with FRY in more than 6 cancer types. Because this analysis shows association rather than direction, both FRY-to-partner and partner-to-FRY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRY versus CRMP1 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRY→partner) and Y-score (partner→FRY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCRMP1 →+0.818+0.922<.001<.00137
LUADDDX21_S121 →-0.788-0.625<.001<.00137
HNSCEIF2S2 →-0.200-0.650<.001.00437
CCRCCTLN1_S2040 →+0.601+0.927<.001<.00137
BRCARPL3 →-0.325-0.966<.001<.00137
CCRCCRPL5 →-0.263-0.862<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 23,309 associations by consensus.

FRY vs CRMP1 — LSCC

Per-sample scatter of FRY vs CRMP1 in LSCC (Pearson r = 0.45).

Explore this scatter interactively →

Exploration