FRY

Across TCGA patient cohorts, FRY protein abundance is significantly associated with the RNA expression of many other genes, with 13,095 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FRY-associated genes across cancer lineages are FRY-AS1, PPFIA2, and ZNF540. Each is linked with FRY in more than 6 cancer types. Because this analysis shows association rather than direction, both FRY-to-partner and partner-to-FRY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRY versus FRY-AS1 in HNSC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRY→partner) and Y-score (partner→FRY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FRY-AS1 →	+1.307	+0.513	<.001	<.001	3	7
GBM	PPFIA2 →	+1.383	+0.292	<.001	.002	3	6
LUAD	ZNF540 →	+0.693	+0.275	<.001	<.001	3	6
BRCA	REPS2 →	+1.444	+0.416	<.001	<.001	3	6
GBM	PDE1A →	+0.829	+0.272	<.001	.007	3	5
HNSC	MYOZ3 →	+0.786	+0.416	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,095 associations by consensus.

FRY vs FRY-AS1 — HNSC

Explore this scatter interactively →