FRY

Across TCGA cell cohorts, FRY RNA expression is significantly associated with the go_rna of many other GO terms, with 4,359 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FRY-associated GO terms across cancer lineages are Aerobic respiration, Negative regulation of tubulin deacetylation, and Negative regulation of myoblast fusion. Each is linked with FRY in more than 9 cancer types. Because this analysis shows association rather than direction, both FRY-to-partner and partner-to-FRY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by FRY-low versus FRY-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FRY→partner) and Y-score (partner→FRY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Aerobic respiration →	+0.089	+1.376	.001	.003	3	10
BLOOD_Lymphoma	Negative regulation of tubulin deacetylation →	+0.974	+2.267	<.001	<.001	3	10
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.126	+1.223	.001	<.001	3	9
OESOPHAGUS	ATP biosynthetic process →	+0.126	+1.130	.001	<.001	3	9
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.150	+1.265	.002	.001	3	8
SOFT_TISSUE	Regulation of alternative mRNA splicing, via spliceosome →	+0.083	+1.336	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,359 associations by consensus.

Aerobic respiration by FRY expression — LUNG_SCLC

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