FRS3

Across TCGA patient cohorts, FRS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,768 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FRS3-associated proteins across cancer lineages are RPS6, SEC24A, and SMC1A. Each is linked with FRS3 in more than 4 cancer types. Because this analysis shows association rather than direction, both FRS3-to-partner and partner-to-FRS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRS3 versus RPS6 in GBM, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRS3→partner) and Y-score (partner→FRS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPS6 →	-0.384	-0.275	<.001	.001	3	5
CCRCC	SEC24A →	-0.301	-0.275	.001	.001	3	5
BRCA	SMC1A →	+0.201	+0.465	.002	.007	3	5
LSCC	MYEF2 →	+0.826	+0.437	<.001	<.001	3	5
LSCC	DNAJC1 →	-0.368	-0.442	<.001	<.001	3	5
BRCA	HNRNPR →	+0.223	+0.648	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,768 associations by consensus.

FRS3 vs RPS6 — GBM

Explore this scatter interactively →