FRS2

Across TCGA patient cohorts, FRS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,951 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FRS2-associated proteins across cancer lineages are MYG1, CAND1, and MLKL. Each is linked with FRS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FRS2-to-partner and partner-to-FRS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRS2 versus MYG1 in HNSC, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRS2→partner) and Y-score (partner→FRS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYG1 →	+0.260	+0.529	<.001	.009	3	6
OV	CAND1 →	+0.388	+0.868	.004	<.001	3	5
BRCA	MLKL →	-0.582	-1.059	<.001	<.001	3	4
GBM	MYO1F →	-0.513	-0.406	<.001	.001	3	4
HNSC	ZFR →	+0.257	+0.666	<.001	.005	2	5
CCRCC	SSR3_S105 →	-0.736	-0.282	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,951 associations by consensus.

FRS2 vs MYG1 — HNSC

Explore this scatter interactively →