FRRS1L

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FRRS1L mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FRRS1L data layer compared with 23 for mass-spec protein.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher FRRS1L mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FRRS1L expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

GBM are the cancer types where FRRS1L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
GBMDFSQuartileAll0.8460.612.0017view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

FRRS1L–GBM (DFS)

Kaplan–Meier survival curve for FRRS1L mass-spec protein-high vs -low samples in GBM.

Open the GBM breakdown →

Exploration