FRRS1L

Across TCGA patient cohorts, FRRS1L mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FRRS1L-associated genes across cancer lineages are ERK2, Annexin-1, and STAT5a. Each is linked with FRRS1L in more than 1 cancer types. Because this analysis shows association rather than direction, both FRRS1L-to-partner and partner-to-FRRS1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by FRRS1L-low versus FRRS1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRRS1L→partner) and Y-score (partner→FRRS1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.209	+3.169	.048	.020	3	1
UCEC	Annexin-1 →	+0.643	+3.169	.026	.020	1	2
UCEC	STAT5a →	+0.594	+3.169	.006	.020	1	1
UCEC	CD20 →	+0.152	+3.169	.035	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ERK2 by FRRS1L expression — UCEC

Explore this box plot interactively →