FRRS1

Across TCGA pan-cancer cohorts, FRRS1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FRRS1 data layer compared with 24 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher FRRS1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FRRS1 expression acts as an unfavorable survival marker.

ESCA and MESO are the cancer types where FRRS1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.124	0.703	<.001	30	view →
MESO	OS	Median	II,III,IV	0.180	0.560	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

FRRS1–ESCA (OS)

Open the ESCA breakdown →