FRRS1

Across TCGA pan-cancer cohorts, FRRS1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FRRS1 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FRRS1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FRRS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, PDAC, and LSCC are the cancer types where FRRS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.784	.002	60	view →
PDAC	DFS	Tertile	All	0.681	0.906	.013	12	view →
LSCC	DFS	Quartile	III,IV	1.000	0.210	.006	11	view →
CCRCC	OS	Median	III,IV	0.516	0.811	.036	2	view →
HNSC	DFS	Quartile	II,III,IV	0.745	0.537	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FRRS1–UCEC (OS)

Open the UCEC breakdown →