FRMPD4

Across TCGA cell cohorts, FRMPD4 mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FRMPD4-associated genes across cancer lineages are OR13C7, NUTM2F, and TRIM50. Each is linked with FRMPD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FRMPD4-to-partner and partner-to-FRMPD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13C7 grouped by FRMPD4-low versus FRMPD4-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMPD4→partner) and Y-score (partner→FRMPD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR13C7 →	+0.038	+5.369	<.001	.004	3	1
CNS	NUTM2F →	+0.022	+3.584	.006	.004	3	1
CNS	TRIM50 →	+0.037	+3.432	.008	.007	3	1
CNS	CCDC42 →	+0.157	+2.906	.005	.009	3	1
CNS	TMEM150B →	+0.058	+3.000	.003	.007	3	1
CNS	KRTAP5-5 →	+0.010	+4.035	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

OR13C7 by FRMPD4 expression — SOFT_TISSUE

Explore this box plot interactively →