FRMPD1

Across TCGA cell cohorts, FRMPD1 mutation is significantly associated with the RNA expression of many other genes, with 941 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FRMPD1-associated genes across cancer lineages are OR11H12, GOLGA6L6, and LEXM. Each is linked with FRMPD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FRMPD1-to-partner and partner-to-FRMPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H12 grouped by FRMPD1-low versus FRMPD1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMPD1→partner) and Y-score (partner→FRMPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR11H12 →	+0.040	+4.222	<.001	.007	3	2
SOFT_TISSUE	GOLGA6L6 →	+0.009	+4.369	<.001	.008	3	2
SKIN	LEXM →	+0.089	+3.443	<.001	.009	3	2
CNS	DUXA →	+0.047	+4.196	<.001	.001	3	2
BLOOD_Leukemia	VWC2 →	+0.328	+3.551	.004	.009	3	2
BONE	TAS2R39 →	+0.023	+5.169	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 941 associations by consensus.

OR11H12 by FRMPD1 expression — SOFT_TISSUE

Explore this box plot interactively →