FRMD8

Across TCGA patient cohorts, FRMD8 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,141 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FRMD8-associated proteins across cancer lineages are ACO2, CTNND1_S920, and TMED2. Each is linked with FRMD8 in more than 3 cancer types. Because this analysis shows association rather than direction, both FRMD8-to-partner and partner-to-FRMD8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRMD8 versus ACO2 in GBM, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMD8→partner) and Y-score (partner→FRMD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACO2 →	-0.319	-0.345	<.001	<.001	3	4
HNSC	CTNND1_S920 →	+0.376	+0.596	.002	.004	3	4
CCRCC	TMED2 →	-0.332	-0.368	<.001	<.001	3	4
GBM	WDR7 →	-0.251	-0.326	.001	.001	3	4
CCRCC	PRDX4 →	-0.468	-0.476	<.001	<.001	3	3
LSCC	PRRC1 →	-0.270	-0.541	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,141 associations by consensus.

FRMD8 vs ACO2 — GBM

Explore this scatter interactively →