FRMD5

Across TCGA patient cohorts, FRMD5 protein abundance is significantly associated with the RNA expression of many other genes, with 1,040 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FRMD5-associated genes across cancer lineages are GAPDHP55, TNNT1, and DNM1. Each is linked with FRMD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both FRMD5-to-partner and partner-to-FRMD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRMD5 versus GAPDHP55 in GBM, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMD5→partner) and Y-score (partner→FRMD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GAPDHP55 →	+1.315	+0.827	<.001	<.001	3	2
LUAD	TNNT1 →	+4.081	+1.089	<.001	<.001	3	1
LUAD	DNM1 →	+0.512	+0.734	.006	<.001	3	1
LUAD	BAG1 →	-0.875	-1.028	.003	.007	3	1
LUAD	MPP2 →	+0.981	+0.786	.001	.004	3	1
LUAD	ULBP1 →	+0.664	+0.761	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,040 associations by consensus.

FRMD5 vs GAPDHP55 — GBM

Explore this scatter interactively →