FRMD5

Across TCGA cell cohorts, FRMD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,615 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FRMD5-associated GO terms across cancer lineages are Hepatocyte growth factor receptor signaling pathway, White fat cell proliferation, and Cellular response to environmental stimulus. Each is linked with FRMD5 in more than 11 cancer types. Because this analysis shows association rather than direction, both FRMD5-to-partner and partner-to-FRMD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hepatocyte growth factor receptor signaling pathway grouped by FRMD5-low versus FRMD5-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMD5→partner) and Y-score (partner→FRMD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Hepatocyte growth factor receptor signaling pathway →	+0.315	+1.329	<.001	<.001	3	12
BLOOD_Leukemia	White fat cell proliferation →	-0.931	-0.512	.001	<.001	3	11
LUNG_NSCLC_LUSC	Cellular response to environmental stimulus →	+0.052	+1.248	.003	.009	2	11
BREAST	Regulation of plasminogen activation →	+0.248	+1.031	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Cellular response to abiotic stimulus →	+0.052	+1.248	.003	.009	2	11
BREAST	Nucleus organization →	+0.066	+0.873	.002	.005	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,615 associations by consensus.

Hepatocyte growth factor receptor signaling pathway by FRMD5 expression — BREAST

Explore this box plot interactively →