FRMD4A

Across TCGA patient cohorts, FRMD4A RNA expression is significantly associated with the protein abundance of many other proteins, with 11,933 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FRMD4A-associated proteins across cancer lineages are VIM, SRP68, and FRMD4A_S335. Each is linked with FRMD4A in more than 5 cancer types. Because this analysis shows association rather than direction, both FRMD4A-to-partner and partner-to-FRMD4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRMD4A versus VIM in PDAC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMD4A→partner) and Y-score (partner→FRMD4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	VIM →	+0.483	+0.354	<.001	<.001	3	6
LUAD	SRP68 →	-0.201	-0.276	<.001	.002	3	6
GBM	FRMD4A_S335 →	+0.834	+0.803	<.001	<.001	3	6
LSCC	FRMD4A_S727 →	+1.134	+1.169	<.001	<.001	3	6
OV	TRAP1 →	-0.421	-0.594	.002	.003	3	5
OV	QARS1 →	-0.243	-0.650	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,933 associations by consensus.

FRMD4A vs VIM — PDAC

Explore this scatter interactively →