FRMD4A

Across TCGA patient cohorts, FRMD4A protein abundance is significantly associated with the RNA expression of many other genes, with 8,803 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FRMD4A-associated genes across cancer lineages are GYPC, PLCL2, and RASL10A. Each is linked with FRMD4A in more than 3 cancer types. Because this analysis shows association rather than direction, both FRMD4A-to-partner and partner-to-FRMD4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRMD4A versus GYPC in GBM, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMD4A→partner) and Y-score (partner→FRMD4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GYPC →	+0.843	+0.286	<.001	.009	3	4
LSCC	PLCL2 →	+0.658	+0.403	<.001	<.001	3	4
GBM	RASL10A →	+0.902	+0.397	<.001	<.001	3	3
UCEC	TACC1 →	+0.566	+0.313	.009	.005	3	3
UCEC	CNST →	+0.371	+0.278	.005	.003	3	3
GBM	IGSF22 →	+0.380	+0.277	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,803 associations by consensus.

FRMD4A vs GYPC — GBM

Explore this scatter interactively →